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The New England Journal of Medicine: Search Results in Rheumatology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Rheumatology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Psoriatic Arthritis
01/01/70 - Psoriasis is a common skin disease that is associated with multiple coexisting conditions. The most prevalent coexisting condition, psoriatic arthritis, develops in up to 30% of patients with psoriasis and is characterized by diverse clinical features, often resulting in delayed diagnosis and…

Case 6-2017: A 57-Year-Old Woman with Fatigue, Sweats, Weight Loss, Headache, and Skin Lesions
01/01/70 - Presentation of Case. Dr. Kevin J. Heaton (Medicine): A 57-year-old woman was seen in the outpatient rheumatology clinic of this hospital because of fatigue, night sweats, weight loss, headache, diffuse abdominal pain, and skin lesions. The patient had been well until approximately 24 months before…

Inhibiting Plasma Kallikrein for Hereditary Angioedema Prophylaxis
01/01/70 - Hereditary angioedema with C1 inhibitor deficiency is a rare genetic disease that is characterized by recurrent swelling episodes, typically affecting the subcutaneous or submucosal tissues of the hands and feet, abdomen, face, larynx, or genitourinary tract. Swelling of the larynx can be…

Kallikrein Inhibition for Hereditary Angioedema
01/01/70 - Management of hereditary angioedema due to C1 inhibitor deficiency has evolved. During the past 10 years, those affected have progressed from underrecognized disability and premature death, through evidence-based hospital treatment, toward self-administration and independence from unscheduled…

Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis
01/01/70 - Rheumatoid arthritis is a systemic autoimmune disease characterized by inflammatory synovitis and progressive joint destruction, which are associated with severe disability and increased mortality. Progress in treatment with the use of conventional synthetic disease-modifying antirheumatic drugs…

AA Amyloidosis and IgG4-Related Disease
01/01/70 - To the Editor: Here, we describe a patient with renal amyloid A (AA) amyloidosis that was apparently associated with IgG4-related disease. A 53-year-old man with long-standing malaise and fatigue had a slow-growing mesenteric mass (5 cm in diameter) that had been present 16 years earlier on the…

Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis
01/01/70 - Nonsteroidal antiinflammatory drugs (NSAIDs) were introduced in the 1960s and became the most widely prescribed class of drugs in the world, with more than 100 million prescriptions issued annually in the United States alone. NSAIDs inhibit cyclooxygenase (COX), which reduces pain and inflammation…

Safety of Nonsteroidal Antiinflammatory Drugs
01/01/70 - Nonsteroidal antiinflammatory drugs (NSAIDs), one of the most widely used classes of drugs in the world, are effective antiinflammatory, analgesic, and antipyretic agents. Although they differ from one another in chemical class, all inhibit the synthesis of prostaglandins. Because prostaglandins…

Acute Rheumatic Fever with Erythema Marginatum
01/01/70 - Figure 1.

Fulminant Myocarditis with Combination Immune Checkpoint Blockade
01/01/70 - Immune checkpoint inhibitors have transformed the treatment of several cancers by releasing restrained antitumor immune responses. Ipilimumab, an anti?cytotoxic T-lymphocyte?associated antigen 4 (CTLA-4) antibody, and nivolumab, an anti?programmed death-1 (PD-1) antibody, have individually improved…

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