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The New England Journal of Medicine: Search Results in Infectious Disease
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Infectious Disease. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Efficacy of Recombinant Influenza Vaccine in Adults 50 Years of Age or Older
01/01/70 - Reducing the burden of influenza disease requires improved vaccines, and a recombinant influenza vaccine may contribute to this public-health goal. This vaccine contains recombinant hemagglutinin (HA) proteins produced in a serum-free medium by expresSF+ cells. These cells contain recombinant…

A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis
01/01/70 - The dimorphic fungus Talaromyces (previously Penicillium) marneffei causes a life-threatening mycosis in immunocompromised persons living in or traveling to Southeast Asia, China, and India. Talaromycosis (previously penicilliosis) is a major cause of human immunodeficiency virus (HIV)?related…

State Sepsis Mandates ? A New Era for Regulation of Hospital Quality
01/01/70 - Sepsis is a major cause of illness and death in the United States, affecting more than 1.5 million Americans each year at an annual cost of over $20 billion. To improve outcomes of sepsis, policymakers are increasingly using regulatory mechanisms intended to provide incentives to clinicians and…

Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients
01/01/70 - To the Editor: Waiting times for kidney transplants exceed 3 to 5 years in many parts of the United States. Yet more than 500 high-quality kidneys from deceased donors with hepatitis C virus (HCV) infection are discarded annually. Direct-acting antiviral agents, which are associated with high HCV…

Strongyloides stercoralis Hyperinfection
01/01/70 - Figure 1.

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis
01/01/70 - More than 1.5 million cases of sepsis occur in the United States annually, and many patients with sepsis present to the emergency department. International clinical practice guidelines and the Centers for Medicare and Medicaid Services (CMS) recommend the prompt identification of sepsis and…

Early, Goal-Directed Therapy for Septic Shock ? A Patient-Level Meta-Analysis
01/01/70 - In 2001, Rivers and colleagues reported on a 263-patient, single-center, randomized, controlled trial of early, goal-directed therapy (EGDT) versus usual care in patients presenting with septic shock to an urban emergency department in the United States. EGDT is a 6-hour resuscitation protocol for…

Management of Septic Shock
01/01/70 - Ms. Jones has been admitted to the ICU with septic shock and is receiving vasopressors to elevate her mean arterial pressure. Shortly after her arrival, her condition deteriorates, and intubation and mechanical ventilation are initiated because of acute lung injury. The increased lactate level and…

Reviving a Drug for Tuberculosis?
01/01/70 - The early days of tuberculosis drug development produced several drugs that now are used only rarely. Many are poorly effective or associated with common or serious toxic effects. For example, because of toxic effects seen at effective concentrations, ethionamide has been relegated to use in…

Spiraling Out of Control
01/01/70 - Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader (regular type). The authors? commentary follows. Stage. A 22-year-old man presented to the…

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