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The New England Journal of Medicine: Search Results in Infectious Disease
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Infectious Disease. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Improved Titers against Influenza Drift Variants with a Nanoparticle Vaccine
01/01/70 - To the Editor: Paules et al. recently advocated for the development of influenza vaccines "that will protect against seasonal influenza drift variants" and "not be subject to the limitations of egg-based vaccine technology." Improving vaccine responses against A(H3N2) viruses has been a challenge…

Substitute Decision Making in End-of-Life Care
01/01/70 - Three days ago, you were called to the intensive care unit (ICU) to examine Ms. Smith, a 70-year-old woman who had presented to the emergency department earlier that day with progressive shortness of breath. Ms. Smith had reported fatigue, progressive dyspnea, and intermittent fevers over the…

Effect of Dengue Serostatus on Dengue Vaccine Safety and Efficacy
01/01/70 - The first dengue vaccine ? the recombinant, live, attenuated, tetravalent dengue vaccine (CYD-TDV) ? was licensed on the basis of three efficacy trials in the Asia-Pacific region and Latin America. After an excess of hospitalizations for dengue among children who had been vaccinated at 2 to 5 years…

Trolleyology and the Dengue Vaccine Dilemma
01/01/70 - "Trolleyology" refers to a series of moral dilemmas that reveal the tensions between utilitarianism ? the idea that a behavior is moral if its consequences maximize public good ? and our individual intuitions about right and wrong. In a classic scenario, an observer is standing by a railway track…

The Scarlet Virus
01/01/70 - She was a large woman with an easy grin and open demeanor; her threadbare jacket was often askew but always meticulously clean. It was easy to envision her on the front stoops of Baltimore row houses, chatting with neighbors as they numbed their sorrows with hits of speedball, shots in paper bags.…

Fecal Microbiota Transplantation for Primary Clostridium difficile Infection
01/01/70 - To the Editor: Clostridium difficile infection is a major health problem. Antibiotic treatment is associated with a considerable rate of recurrence of infection and is related to the emergence of antibiotic-resistant bacteria. Recently, fecal microbiota transplantation has been shown to be…

ICU Admissions for Sepsis or Pneumonia in Australia and New Zealand in 2017
01/01/70 - To the Editor: Seasonal patterns of presentations to intensive care units (ICUs) in the Southern Hemisphere can inform health care planning for critically ill patients worldwide, as was seen during the H1N1 influenza pandemic in 2009. During the late winter and early spring of 2017, ICUs in…

Innovation for Pandemics
01/01/70 - Over recent decades, the world has seen incredible progress in reducing child mortality and tackling infectious diseases. Thanks to better vaccines and other interventions, child mortality has decreased by more than 50% since 1990. We are on the verge of eradicating polio. HIV is no longer a…

Mortality in Puerto Rico after Hurricane Maria
01/01/70 - The tropical cyclone Hurricane Maria made landfall in Puerto Rico, a territory of the United States, on September 20, 2017. It compounded the destruction caused by Hurricane Irma 2 weeks earlier, damaging roads and interrupting the water supply, electricity, telecommunications networks, and access…

Incidence of Cellulitis among Children with Primary Lymphedema
01/01/70 - To the Editor: Primary lymphedema is increasingly recognized in children, and prevention of tissue damage is the main goal of care. Infections such as cellulitis occur among patients with lymphedema. Data on the incidence of cellulitis among children are lacking; this hampers the assessment of any…

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