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The New England Journal of Medicine: Search Results in Infectious Disease
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Infectious Disease. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Interleukin-12 and Interleukin-23 Blockade in Leukocyte Adhesion Deficiency Type 1
01/01/70 - LAD1 is a primary immunodeficiency resulting from mutations in ITGB2, which encodes the common CD18 subunit of the ?2 integrins; the ?2 integrins are required for the adhesion of neutrophils to endothelium and the transmigration of neutrophils into tissues. Patients with LAD1 typically have…

Fournier?s Gangrene
01/01/70 - Figure 1.

Rotavirus Vaccines ? A New Hope
01/01/70 - Rotavirus gastroenteritis is the leading cause of diarrhea-associated hospitalization and death in children younger than 5 years of age, with more than 85% of the approximately 200,000 annual rotavirus deaths occurring in Africa and Asia. Since improvements in water, sanitation, and hygiene do not…

Incidental Finding of Oleothorax
01/01/70 - Figure 1.

Breaking a Vicious Cycle
01/01/70 - In this issue of the Journal, Moutsopoulos et al. report on a patient with leukocyte adhesion deficiency type 1 (LAD1) who was successfully treated with ustekinumab, a monoclonal antibody to the p40 subunit common to interleukin-12 and interleukin-23. Patients with LAD1 have defective neutrophil…

Efficacy of a Low-Cost, Heat-Stable Oral Rotavirus Vaccine in Niger
01/01/70 - Rotavirus is a leading cause of severe gastroenteritis among young children and is responsible for approximately 37% of deaths from diarrhea among children younger than 5 years of age worldwide. Two live, oral, attenuated rotavirus vaccines (Rotarix, GlaxoSmithKline, and RotaTeq, Merck) have met…

Early, Goal-Directed Therapy for Septic Shock ? A Patient-Level Meta-Analysis
01/01/70 - In 2001, Rivers and colleagues reported on a 263-patient, single-center, randomized, controlled trial of early, goal-directed therapy (EGDT) versus usual care in patients presenting with septic shock to an urban emergency department in the United States. EGDT is a 6-hour resuscitation protocol for…

Case 8-2017: A 39-Year-Old Zimbabwean Man with a Severe Headache
01/01/70 - Presentation of Case. Dr. A. Tariro Makadzange: A 39-year-old man was admitted to a large, urban tertiary-care hospital in Zimbabwe (where a physician affiliated with this hospital works) because of a severe headache. The patient had been in his usual health until approximately 1 month before…

Chimpanzee Adenovirus Vector Ebola Vaccine
01/01/70 - In August 2014, the World Health Organization declared the epidemic of Ebola virus disease (EVD) in West Africa to be a public health emergency of international concern. This was the first time in more than 20 outbreaks since EVD was identified in 1976 that such a declaration had been made. The…

Post-Babesiosis Warm Autoimmune Hemolytic Anemia
01/01/70 - Babesiosis is a tickborne zoonotic disease that is caused by intraerythrocytic protozoa of the genus babesia. In the northeastern and upper midwestern regions of the United States, where Babesia microti is endemic, the incidence of babesiosis has increased dramatically in the past 10 years,…

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