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The New England Journal of Medicine: Search Results in Pulmonary\Critical Care
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Pulmonary\Critical Care. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis
01/01/70 - Bronchiolitis, an acute lower airway lung disease that is generally caused by respiratory viruses, is the most common reason worldwide for nonelective hospital admission in infants. In the United States, bronchiolitis is responsible for $1.7 billion in hospitalization costs annually. In Australia…

Case 8-2018: A 55-Year-Old Woman with Shock and Labile Blood Pressure
01/01/70 - Presentation of Case. Dr. Nathalie Roy: A 55-year-old woman was transferred to this hospital for evaluation and treatment of cardiogenic shock. Approximately 4 months before presentation, the patient was admitted to a hospital in her home state for "pounding" in her chest, nausea, and diaphoresis…

Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations
01/01/70 - Asthma is one of the most common chronic diseases, with an estimated 300 million people affected worldwide. Acute exacerbations of asthma are frightening for patients, cause considerable illness and death, and account for a large proportion of the overall costs related to asthma. Although plans for…

Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations
01/01/70 - Asthma exacerbations are common events, particularly in school-age children. Exacerbations are costly and are associated with considerable complications. In addition, asthma exacerbations may lead to progressive loss of lung function and greater asthma severity over time. Although conventional…

Escalating Inhaled Glucocorticoids to Prevent Asthma Exacerbations
01/01/70 - Inhaled glucocorticoids are pivotal to achieve asthma control and disease stability in both children and adults; despite their use, with or without other treatments, many patients with asthma have ongoing episodic disease exacerbations. Often, these are linked to provocative factors such as viral…

Where There?s Wildfire, There?s Smoke
01/01/70 - With the undeniable march of climate change, the danger of catastrophic wildfires is increasing around the globe, with such fires occurring in Australia, Canada, Chile, Indonesia, Portugal, and Russia, as well as the United States, over the past decade. Large forest fires in the western United…

Balanced Crystalloids versus Saline in Critically Ill Adults
01/01/70 - Intravenous crystalloid solutions are commonly administered in critical care, yet the question of whether crystalloid composition affects patient outcomes remains unanswered. Historically, 0.9% sodium chloride (saline) has been the most commonly administered intravenous fluid. Data suggest that…

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock
01/01/70 - Sepsis, which has been identified by the World Health Organization as a global health priority, has no proven pharmacologic treatment, other than the appropriate antibiotic agents, fluids, and vasopressors as needed; reported death rates among hospitalized patients range between 30% and 45%.…

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock
01/01/70 - Septic shock is characterized by a dysregulated host response to infection, resulting in life-threatening circulatory, cellular, and metabolic abnormalities. The short-term mortality is approximately 45 to 50%, and 50% of survivors of sepsis may have subsequent long-term cognitive decline. Apart…

Balanced Crystalloids versus Saline in Noncritically Ill Adults
01/01/70 - Administration of intravenous isotonic crystalloids is one of the most common medical therapies, with routine use in emergency departments, hospital wards, intensive care units (ICUs), and operating rooms. However, it is not known whether the composition of isotonic crystalloid fluid has an effect…

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