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The New England Journal of Medicine: Search Results in Hematology\Oncology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Hematology\Oncology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Venetoclax?Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia
01/01/70 - Relapsed or refractory chronic lymphocytic leukemia remains incurable, despite advances in treatment over the past 5 years. When disease progression occurs, especially after treatment with DNA-damaging agents, chronic lymphocytic leukemia cells serially accumulate adverse biologic features and…

Case 9-2018: A 55-Year-Old Man with HIV Infection and a Mass on the Right Side of the Face
01/01/70 - Presentation of Case. Dr. Robert H. Goldstein (Medicine): A 55-year-old man with Crohn?s disease and a new diagnosis of human immunodeficiency virus type 1 (HIV-1) infection was seen in the infectious diseases clinic of this hospital because of a mass on the right side of the face. Fifteen days…

Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer
01/01/70 - The World Health Organization (WHO) categorized Helicobacter pylori as a group I carcinogen for gastric cancer in 1994 on the basis of observational studies. In 2000, a study showed a preventive effect of H. pylori treatment on gastric cancer in Mongolian gerbils. However, the level of evidence…

Helicobacter pylori Treatment for Gastric Cancer Prevention
01/01/70 - Gastric cancer has become a potentially preventable disease through eradication of Helicobacter pylori. However, issues that are associated with "screen and treat" strategies ? their effectiveness, proper selection of populations to target, and cost?benefit considerations ? continue to interfere…

Hazards of Hazard Ratios ? Deviations from Model Assumptions in Immunotherapy
01/01/70 - To the Editor: Summary statistics, such as hazard ratios, that are based on models may be difficult to interpret if there are substantial departures from key assumptions, including the assumption of proportionality of hazard functions. Recent cancer immunotherapy trials provide a contemporary…

Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma
01/01/70 - Sunitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, is a standard of care for first-line treatment of advanced renal-cell carcinoma. In a large, randomized, phase 3 trial involving previously untreated patients, the median progression-free survival with sunitinib was…

MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis
01/01/70 - Men with a clinical suspicion of prostate cancer on the basis of an elevated prostate-specific antigen (PSA) level or an abnormal digital rectal examination are typically offered a standard transrectal ultrasonography?guided biopsy of the prostate during which 10 to 12 cores are obtained. This…

HIV-Associated Cancers and Related Diseases
01/01/70 - Clusters of cases of pneumocystis pneumonia and Kaposi?s sarcoma in New York and California in men who had sex with men were early harbingers of the acquired immunodeficiency syndrome (AIDS) epidemic. The syndrome was also soon noted to be associated with a high incidence of aggressive B-cell…

Tumors and Transformations
01/01/70 - It happened 21 years ago, near the end of a night on-call. Around 5 a.m. the emergency department physician paged radiology and requested an ultrasound on a 41-year-old male with right upper quadrant pain. I walked down the hall and entered the exam room. A man lay on his back on a gurney and a…

Balancing Safety and Innovation for Cell-Based Regenerative Medicine
01/01/70 - Regenerative medicine is a field that involves replacing, engineering, or regenerating human cells, tissues, or organs to establish, restore, or enhance normal function. It is an area with great promise that goes directly to the role of the Food and Drug Administration (FDA) in helping to…

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