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The New England Journal of Medicine: Search Results in Hematology\Oncology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Hematology\Oncology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Pleural Disease
01/01/70 - The pleural space is defined by the visceral pleura, which covers the lung, and the parietal pleura, which covers the chest wall, diaphragm, and mediastinum. It is estimated that pleural effusion develops in more than 1.5 million patients each year in the United States, with the majority of cases…

Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty
01/01/70 - Deep-vein thrombosis and pulmonary embolism (collectively known as venous thromboembolism) are well-recognized complications after total hip or total knee arthroplasty. The perioperative administration of anticoagulant prophylaxis has proved to reduce the rates of death and complications associated…

Case 6-2018: A 35-Year-Old Woman with Headache, Subjective Fever, and Anemia
01/01/70 - Presentation of Case. Dr. J. Sawalla Guseh II: A 35-year-old woman with a history of Crohn?s disease was admitted to this hospital with headache, subjective fever, and anemia. The patient had been in her usual state of health until 1 week before admission, when headache, fatigue, and myalgias…

Efficacy of Larotrectinib in TRK Fusion?Positive Cancers in Adults and Children
01/01/70 - The neurotrophic receptor tyrosine kinase genes NTRK1, NTRK2, and NTRK3 encode the tropomyosin receptor kinase (TRK) proteins TRKA, TRKB, and TRKC, respectively. After embryogenesis, TRK expression is limited primarily to the nervous system, where these kinases help regulate pain, proprioception,…

Hybrid Strategy to Prevent Venous Thromboembolism after Joint Arthroplasty
01/01/70 - Total hip and total knee replacement procedures offer the potential to relieve pain and disability, but both surgeries expose patients to a substantial risk of venous thromboembolism. Most experts agree that postoperative pharmacologic prophylaxis is warranted, but different clinical practice…

Developing Anticancer Drugs in Orphan Molecular Entities ? A Paradigm under Construction
01/01/70 - Genomic characterization of cancers has shown that some oncogenic alterations occur at very low frequency and are shared across tumor types. For example, NTRK translocations mediate malignant transformation and are observed in less than 1% of cancers and in more than 20 cancer types. The genes…

Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism
01/01/70 - Venous thromboembolism is a common complication of cancer and its therapy. Treatment of cancer-associated venous thromboembolism is challenging, and the risks of recurrent thrombosis and bleeding are higher among patients with cancer than among those without cancer. These two complications are…

Metastatic Prostate Cancer
01/01/70 - Care for men with prostate cancer is a major global health care challenge, compounded by an aging population and increasing frequency of diagnosis. The priorities today are similar to those in the recent past: minimizing overtreatment of indolent disease and improving outcomes for patients with…

Case 5-2018: A 63-Year-Old Man with Confusion after Stem-Cell Transplantation
01/01/70 - Presentation of Case. Dr. Joshua A. Cohen (Medicine): A 63-year-old man was admitted to this hospital with confusion and weakness 5 months after he had undergone allogeneic stem-cell transplantation for chronic lymphocytic leukemia (CLL). The patient had been generally well until 2 years before…

Innervating Prostate Cancer
01/01/70 - Thirty years ago, Sir James W. Black shared the Nobel Prize in Physiology or Medicine for his contribution to the development of propranolol (a beta-blocker) and cimetidine (a histamine H2 blocker). Since that time, beta-blockers have been and remain widely used as antihypertensive drugs. An…

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