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The New England Journal of Medicine: Search Results in Gastroenterology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Gastroenterology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients
01/01/70 - To the Editor: Waiting times for kidney transplants exceed 3 to 5 years in many parts of the United States. Yet more than 500 high-quality kidneys from deceased donors with hepatitis C virus (HCV) infection are discarded annually. Direct-acting antiviral agents, which are associated with high HCV…

Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection
01/01/70 - The majority of patients who are chronically infected with hepatitis C virus (HCV) can now be successfully treated with drugs that directly target viral replication. Combination regimens of direct-acting antiviral agents (DAAs) provide rates of sustained virologic response exceeding 90%, regardless…

IDH2 Mutation in a Patient with Metastatic Colon Cancer
01/01/70 - To the Editor: Detection of circulating tumor DNA (ctDNA) in cell-free DNA (cfDNA) is an emerging noninvasive strategy for tumor profiling. However, an understanding of potential biologic interference associated with this new technique is still evolving. Here, we present a case that posed a…

Reversal of Autoimmune Toxicity and Loss of Tumor Response by Interleukin-17 Blockade
01/01/70 - To the Editor: Patients with autoimmune diseases have typically been excluded from immunotherapy clinical trials, although recent evidence suggests that the benefits of checkpoint therapy may outweigh the risks of autoimmune flare-ups in carefully selected patients who have a high probability of…

Case 14-2017: A 20-Year-Old Man with Pain and Swelling of the Left Calf and a Purpuric Rash
01/01/70 - Presentation of Case. Dr. Lauren R. Zeitels (Medicine): A 20-year-old man was seen in an outpatient clinic of this hospital because of pain and swelling of the left calf and a purpuric rash. The patient had been well until 3 weeks before presentation to this hospital, when sore throat,…

Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis
01/01/70 - Ulcerative colitis is characterized by an increased frequency of bowel movements and bloody diarrhea, which has a negative effect on quality of life. Current therapies for ulcerative colitis include mesalamine, glucocorticoids, thiopurines, and antagonists to tumor necrosis factor (TNF) and ?4?7…

Tofacitinib for Ulcerative Colitis ? A Promising Step Forward
01/01/70 - Ulcerative colitis is a chronic inflammatory disease of the colon that is often debilitating, commonly occurs at a young age, and has a serious effect on overall health and quality of life. The use of currently available medications for moderate-to-severe ulcerative colitis results in sustained…

Candida Esophagitis
01/01/70 - Figure 1.

Case 10-2017 ? A 6-Month-Old Boy with Gastrointestinal Bleeding and Abdominal Pain
01/01/70 - Presentation of Case. Dr. Akash Gupta (Medicine and Pediatrics): A 6-month-old boy was seen in the emergency department of this hospital because of gastrointestinal bleeding and abdominal pain. The patient had been in his usual state of health until 2 days before presentation, when his parents…

Multispectral Optoacoustic Tomography for Assessment of Crohn?s Disease Activity
01/01/70 - To the Editor: In chronic inflammatory diseases, uncontrolled inflammation is associated with increased rates of hospitalization, complications, and death. Because of the potential severity of these conditions, there is an increased demand for new diagnostic approaches. Multispectral optoacoustic…

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