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The New England Journal of Medicine: Search Results in Cardiology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Cardiology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation
01/01/70 - In determining the best approach for antithrombotic therapy in patients with atrial fibrillation who are undergoing percutaneous coronary intervention (PCI), it can be difficult to balance the prevention of thrombosis with the risk of bleeding. Oral anticoagulation is indicated in patients with…

Evaluation and Management of Lower-Extremity Ulcers
01/01/70 - Lower-extremity ulcers are very common, with an estimated prevalence of 1 to 2% among U.S. adults, and they have a major effect on public health. Lower-extremity ulcers are divided into two groups ? leg ulcers and foot ulcers ? because of differences in causes, pathogenesis, and treatment. Even…

Triple Therapy for Atrial Fibrillation after PCI
01/01/70 - The management of atrial fibrillation in patients who have undergone percutaneous coronary intervention (PCI) for the treatment of coronary-artery disease is a common and difficult challenge. In patients with atrial fibrillation, oral anticoagulation is administered to reduce the risk of stroke. In…

Takotsubo Cardiomyopathy
01/01/70 - Figure 1.

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease
01/01/70 - Despite the use of effective secondary prevention strategies, 5 to 10% of patients with cardiovascular disease have recurrent events each year. When used for secondary prevention, aspirin results in a 19% lower risk of major adverse cardiovascular events and a 9% lower risk of cardiovascular death…

Challenges in the Design and Interpretation of Noninferiority Trials
01/01/70 - Noninferiority clinical trials have become a major tool for the evaluation of drugs, devices, biologics, and other medical treatments. Treatment with placebo or with a no-treatment control in a study is not ethical when an effective treatment has already been established. Effective medical…

An Important Step for Thrombocardiology
01/01/70 - It has been known for more than a century that coronary-artery thrombosis is the most common precipitant of acute myocardial infarction and that atherosclerotic plaques in the coronary arteries are often responsible for angina pectoris. When anticoagulants and antiplatelet agents became available,…

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes
01/01/70 - The risk of death from any cause among persons with type 2 diabetes is up to twice that of the general population, and the risk of death from cardiovascular causes is up to four times that of the general population. Improved glycemic control has been shown to improve microvascular outcomes, but a…

Oxygen Therapy in Suspected Acute Myocardial Infarction
01/01/70 - Myocardial infarction is caused by a mismatch of oxygen and substrate supply and demand in the myocardium that leads to ischemia and ultimately to cell death. Therefore, for more than a century, supplemental oxygen has been used routinely in the treatment of patients with suspected acute myocardial…

Indications for and Adverse Effects of Red-Cell Transfusion
01/01/70 - Approximately 11 million units of red cells are transfused annually in the United States, making red-cell transfusion one of the most common medical interventions. Red cells are typically administered as a concentrate, called packed red cells, with a preservative solution (hematocrit, 60%) that…

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