Public Health, Policy, and Training
The New England Journal of Medicine: Search Results in Nephrology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Nephrology. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.
TARGT Gene Therapy Platform for Correction of Anemia in End-Stage Renal Disease
01/01/70 - To the Editor: Anemia in patients with end-stage renal disease who are undergoing hemodialysis is caused, in part, by a reduction in or absence of secretion of endogenous erythropoietin. Recombinant human erythropoietin given intravenously has been associated with an increased risk of…
Preserved Renal-Allograft Function and the PD-1 Pathway Inhibitor Nivolumab
01/01/70 - To the Editor: Inhibition of immune checkpoints with the use of antibodies targeting programmed cell death 1 (PD-1) or monoclonal antibodies against cytotoxic T-lymphocyte?associated antigen 4 (CTLA-4) has been used clinically in patients with various types of cancer. In the limited number of…
After the Party?s Over
01/01/70 - Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader (regular type). The authors? commentary follows. Stage. While driving home from an evening…
Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults
01/01/70 - Epidemiologic studies involving adults have shown that acute kidney injury is associated with increased mortality, prolonged mechanical ventilation, and prolonged length of stay in intensive care units (ICUs). A multinational, prospective study involving 1802 adults initiated the use of Kidney…
Acute Kidney Injury in Critically Ill Children ? An Ominous Legacy
01/01/70 - Children are generally healthy. As we age, however, the chance of having ailments that affect our overall health increases. Recent data from the Centers for Disease Control and Prevention indicate that only 1.3% of children younger than 6 years of age and 2.8% of those 6 to 18 years of age have…
Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy
01/01/70 - Each year, approximately 300,000 persons worldwide are diagnosed with renal-cell carcinoma, resulting in 129,000 deaths. The prognosis for patients with renal-cell carcinoma is dependent on the stage of disease and other risk factors. The 5-year survival rate is 53% for locoregional (stage III)…
Nephron Protection in Diabetic Kidney Disease
01/01/70 - The Clinical Implications of Basic Research series has focused on highlighting laboratory research that could lead to advances in clinical therapeutics. However, the path between the laboratory and the bedside runs both ways: clinical observations often pose new questions for laboratory…
Acetazolamide in Lithium-Induced Nephrogenic Diabetes Insipidus
01/01/70 - To the Editor: The most common cause of acquired nephrogenic diabetes insipidus is long-term lithium treatment. The management of lithium-induced nephrogenic diabetes insipidus is challenging, even when the drug is discontinued and therapy is changed to thiazide diuretics, amiloride, and reduced…
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