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The New England Journal of Medicine: Search Results in Nephrology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Nephrology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Toxic Alcohols
01/01/70 - Poisonings by the toxic alcohols (methanol, ethylene glycol, isopropanol, diethylene glycol, and propylene glycol) can cause cellular dysfunction and death, but symptoms may be nonspecific. Delays in diagnosis increase the risk of irreversible organ damage and death. In this review, we discuss the…

Acute Pyelonephritis in Adults
01/01/70 - Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors? clinical recommendations. Stage. An otherwise…

Case 40-2017: A 32-Year-Old Woman with Headache, Abdominal Pain, Anemia, and Thrombocytopenia
01/01/70 - Presentation of Case. Dr. Emer McGrath (Neurology): A 32-year-old woman was admitted to this hospital in the fall because of severe headache and loss of peripheral vision. The patient had been in her usual state of health until 4 weeks before admission to this hospital, when she underwent elective…

Kidney Diseases Associated with Human Immunodeficiency Virus Infection
01/01/70 - Highly active antiretroviral therapy has led to dramatic improvement in the life expectancy of persons with human immunodeficiency virus (HIV) infection. Approximately 36.7 million people live with HIV infection worldwide, and there were approximately 2.1 million cases of incident HIV infection…

Diuretic Treatment in Heart Failure
01/01/70 - Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of diuretics, among the most frequently used drugs in heart failure, is generally lacking. Fluid…

Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease
01/01/70 - Autosomal dominant polycystic kidney disease (ADPKD) is the fourth leading cause of end-stage kidney disease in adults. When the genes encoding polycystin 1 (PKD1) and polycystin 2 (PKD2) are disrupted, tubular epithelial cells in vasopressin-sensitive distal nephrons and collecting ducts show…

Tolvaptan and Autosomal Dominant Polycystic Kidney Disease
01/01/70 - Approximately half the patients with autosomal dominant polycystic kidney disease (ADPKD), a condition due to deficiency in polycystin 1 or 2, have end-stage kidney disease by 60 years of age. Once progression begins, the mean decline in the estimated glomerular filtration rate (GFR) is…

Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine
01/01/70 - Acute kidney injury associated with the administration of contrast material during angiography can result in death, accelerated progression of underlying chronic kidney disease, and the need for dialysis, along with substantial increases in health care costs. The periprocedural administration of…

ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes
01/01/70 - Children with type 1 diabetes are at higher risk for long-term renal and cardiovascular disease and death than the general population, and adolescence is a period of risk for the development of complications, since adequate glycemic control is difficult to achieve. Rapid increases in albumin…

Nutritional Management of Chronic Kidney Disease
01/01/70 - Chronic kidney disease, defined as evidence of structural or functional renal impairment for 3 or more months, is generally progressive and irreversible, affecting multiple metabolic pathways. Altered protein and energy homeostasis, abnormal protein catabolism, acid?base derangements, and hormonal…

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