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Nejm News Une Mise à Jour The New England Journal of Medicine by Specialties

 


The New England Journal of Medicine: Search Results in Nephrology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Nephrology. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Genetic Drivers of Kidney Defects in the DiGeorge Syndrome
01/01/70 - Deletions on chromosome 22q11.2 are the most common cause of the DiGeorge syndrome (Online Mendelian Inheritance in Man [OMIM] number, 188400) and the velocardiofacial syndrome (OMIM number, 192430) and constitute the most common microdeletion disorder in humans, with an estimated prevalence of 1…

AA Amyloidosis and IgG4-Related Disease
01/01/70 - To the Editor: Here, we describe a patient with renal amyloid A (AA) amyloidosis that was apparently associated with IgG4-related disease. A 53-year-old man with long-standing malaise and fatigue had a slow-growing mesenteric mass (5 cm in diameter) that had been present 16 years earlier on the…

Systemic Therapy for Metastatic Renal-Cell Carcinoma
01/01/70 - Until recently, there was a dearth of effective systemic therapies for kidney cancer. The incidence of the disease steadily increased from 1975 through 2008 and leveled off after 2008. Currently, it is among the 10 most frequently diagnosed cancers in men and women in the United States, with more…

Allocating Organs to Cognitively Impaired Patients
01/01/70 - Should patients? cognitive function be weighed in the allocation of scarce organs? This question has been raised by several highly publicized cases that, on October 12, 2016, culminated in 30 members of the U.S. Congress petitioning the Department of Health and Human Services to "issue guidance on…

TARGT Gene Therapy Platform for Correction of Anemia in End-Stage Renal Disease
01/01/70 - To the Editor: Anemia in patients with end-stage renal disease who are undergoing hemodialysis is caused, in part, by a reduction in or absence of secretion of endogenous erythropoietin. Recombinant human erythropoietin given intravenously has been associated with an increased risk of…

Preserved Renal-Allograft Function and the PD-1 Pathway Inhibitor Nivolumab
01/01/70 - To the Editor: Inhibition of immune checkpoints with the use of antibodies targeting programmed cell death 1 (PD-1) or monoclonal antibodies against cytotoxic T-lymphocyte?associated antigen 4 (CTLA-4) has been used clinically in patients with various types of cancer. In the limited number of…

After the Party?s Over
01/01/70 - Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader (regular type). The authors? commentary follows. Stage. While driving home from an evening…

Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults
01/01/70 - Epidemiologic studies involving adults have shown that acute kidney injury is associated with increased mortality, prolonged mechanical ventilation, and prolonged length of stay in intensive care units (ICUs). A multinational, prospective study involving 1802 adults initiated the use of Kidney…

Acute Kidney Injury in Critically Ill Children ? An Ominous Legacy
01/01/70 - Children are generally healthy. As we age, however, the chance of having ailments that affect our overall health increases. Recent data from the Centers for Disease Control and Prevention indicate that only 1.3% of children younger than 6 years of age and 2.8% of those 6 to 18 years of age have…

Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy
01/01/70 - Each year, approximately 300,000 persons worldwide are diagnosed with renal-cell carcinoma, resulting in 129,000 deaths. The prognosis for patients with renal-cell carcinoma is dependent on the stage of disease and other risk factors. The 5-year survival rate is 53% for locoregional (stage III)…

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