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The New England Journal of Medicine: Search Results in Nephrology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Nephrology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality
01/01/70 - Ambulatory blood-pressure data provide a more comprehensive assessment of blood pressure over the course of a day and have been reported to better predict health outcomes than blood pressure measured in the clinic (clinic blood pressure) or at home. Evidence for the influence of ambulatory blood…

The Value in an Ambulatory Blood-Pressure Registry
01/01/70 - Ambulatory blood-pressure monitoring provides the best confirmation of the presence of hypertension detected in the office setting. A systematic review sponsored by the Agency for Healthcare Research and Quality concluded that "evidence supports ambulatory blood-pressure monitoring as the reference…

Diagnostic Use of Base Excess in Acid?Base Disorders
01/01/70 - For almost 100 years, clinicians have been trying to assess acid?base disturbances accurately and to unravel the mechanisms involved. Many schemes have been introduced to describe acid?base disorders. The three most commonly used methods of quantifying these disorders are the physiological…

Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma
01/01/70 - Sunitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, is a standard of care for first-line treatment of advanced renal-cell carcinoma. In a large, randomized, phase 3 trial involving previously untreated patients, the median progression-free survival with sunitinib was…

Inventing a New Model of Hypertension Care for Black Men
01/01/70 - There are more than 200,000 deaths in the United States each year from heart disease, stroke, and hypertensive disease that could be avoided by timely and effective preventive medical care. The risk of avoidable cardiovascular deaths among black men is 80% higher than that among white men or black…

Immunotherapy in Advanced Renal Cancer ? Is Cure Possible?
01/01/70 - Treatment for advanced renal-cell carcinoma has traced a remarkable arc during the past 25 years. In the 1990s, options included interferon, interleukin-2, megestrol, and 5-fluorouracil chemotherapy. Although a small proportion of patients had durable regression of renal-cell carcinoma with…

Lithium-Induced Nephropathy
01/01/70 - A 59-year-old man with a history of bipolar disorder was admitted to the hospital after a fall. He received a diagnosis of multiple fractures of the head and spine; the fractures were managed nonoperatively. During the hospitalization, his urine output was noted to range from 4 to 6 liters per day.…

Xanthogranulomatous Pyelonephritis
01/01/70 - A 73-year-old woman presented to the emergency department with a 10-day history of fever and lethargy. Her medical history included type 2 diabetes, recurrent urinary tract infection, and weight loss of approximately 13.5 kg during the previous year. Laboratory studies revealed a white-cell count…

Balanced Crystalloids versus Saline in Critically Ill Adults
01/01/70 - Intravenous crystalloid solutions are commonly administered in critical care, yet the question of whether crystalloid composition affects patient outcomes remains unanswered. Historically, 0.9% sodium chloride (saline) has been the most commonly administered intravenous fluid. Data suggest that…

Balanced Crystalloids versus Saline in Noncritically Ill Adults
01/01/70 - Administration of intravenous isotonic crystalloids is one of the most common medical therapies, with routine use in emergency departments, hospital wards, intensive care units (ICUs), and operating rooms. However, it is not known whether the composition of isotonic crystalloid fluid has an effect…

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