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The New England Journal of Medicine: Search Results in Nephrology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Nephrology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
01/01/70 - Type 2 diabetes mellitus is associated with a substantial risk of cardiovascular and renal disease. The use of inhibitors of sodium?glucose cotransporter 2 (SGLT2) results in favorable effects on biomarkers, including glycemia, blood pressure, weight, intrarenal hemodynamics, and albuminuria, and…

IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation
01/01/70 - Although renal transplantation is considered to be the treatment of choice for patients with end-stage renal disease, rates of transplantation remain low among patients with high levels of preformed anti-HLA antibodies. In such cases, the immunologic barrier, which is linked to an increased risk of…

A Bacterial IgG-Degrading Enzyme to Unhinge Antibodies
01/01/70 - The number of patients awaiting renal transplantation heads ever upward (in the United States alone, more than 105,000 patients are currently on the waiting list for a kidney from a deceased donor, according to the United Network for Organ Sharing), and many of those patients are unlikely to…

Perirenal Extramedullary Hematopoiesis
01/01/70 - Figure 1.

Single-Nephron Glomerular Filtration Rate in Healthy Adults
01/01/70 - The glomerular filtration rate (GFR) is considered to be the most important assessment of kidney function. In clinical practice, the total GFR, which is the sum of all the single-nephron GFRs, is determined. Previous studies that have counted glomeruli at autopsy have shown considerable variation…

Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients
01/01/70 - To the Editor: Waiting times for kidney transplants exceed 3 to 5 years in many parts of the United States. Yet more than 500 high-quality kidneys from deceased donors with hepatitis C virus (HCV) infection are discarded annually. Direct-acting antiviral agents, which are associated with high HCV…

Tuberous Sclerosis Complex
01/01/70 - Figure 1.

Acute Kidney Injury in Patients with Cancer
01/01/70 - Acute kidney injury is common in patients with cancer; the incidence and severity vary, depending on the type and stage of cancer, the treatment regimen, and coexisting conditions. In a 7-year Danish study of 37,267 incident cases of cancer, the 1-year risk of acute kidney injury, as defined by the…

Case 12-2017 ? A 34-Year-Old Man with Nephropathy
01/01/70 - Presentation of Case. Dr. Daniel H. Katz (Medicine): A 34-year-old man with hearing impairment was admitted to this hospital because of worsening renal function. The patient had been well until approximately 11 weeks before this admission, when subjective fevers with sweats, fatigue, decreased…

Case 11-2017 ? A 61-Year-Old Woman with Leg Swelling, Back Pain, and Hydronephrosis
01/01/70 - Presentation of Case. Dr. Areej El-Jawahri (Hematology?Oncology): A 61-year-old woman was seen in the emergency department of this hospital because of leg swelling and back pain. The patient had been in her usual health until approximately 3 months before this presentation, when mild swelling of…

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