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The New England Journal of Medicine: Search Results in Neurology\Neurosurgery
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Neurology\Neurosurgery. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Opioid-Prescribing Patterns of Emergency Physicians and Risk of Long-Term Use
01/01/70 - Rates of opioid prescribing and opioid-related overdose deaths have quadrupled in the United States over the past three decades. This epidemic has increasingly affected the elderly Medicare population, among whom rates of hospitalization for opioid overdoses quintupled from 1993 through 2012. The…

Case 3-2017: A 62-Year-Old Man with Cardiac Sarcoidosis and New Diplopia and Weakness
01/01/70 - Presentation of Case. Dr. L. Nicolas Gonzalez Castro (Neurology): A 62-year-old man with sarcoidosis and heart disease was admitted to this hospital because of new-onset diplopia and weakness. The patient was in his usual health until approximately 2 weeks before admission, when nausea, dizziness,…

"Zombie" Outbreak Caused by the Synthetic Cannabinoid AMB-FUBINACA in New York
01/01/70 - Commonly abused drugs are undergoing a period of proliferation and diversification, with a corresponding increase in the challenges faced by emergency and critical care physicians, substance abuse professionals, psychiatrists, and toxicologists. New psychoactive substances provide users with…

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis
01/01/70 - Primary progressive multiple sclerosis accounts for 10 to 15% of the overall population with multiple sclerosis. The course of this disease differs from those of relapsing?remitting and secondary progressive forms of multiple sclerosis in that progression consists mainly of gradual worsening of…

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis
01/01/70 - Despite the availability of several disease-modifying treatments for relapsing forms of multiple sclerosis, patients often continue to have clinical and subclinical disease activity, and neurologic disability continues to accrue. Thus, there is a need for more effective treatments with acceptable…

B-Cell Depletion ? A Frontier in Monoclonal Antibodies for Multiple Sclerosis
01/01/70 - Multiple sclerosis is a disabling autoimmune disease in which immune cells target central nervous system (CNS) antigens, leading to demyelination, glial activation, and subsequent loss of neurons and axons. There are three main subtypes of multiple sclerosis: relapsing?remitting, in which patients…

Variant Creutzfeldt?Jakob Disease in a Patient with Heterozygosity at PRNP Codon 129
01/01/70 - To the Editor: Prions cause lethal neurodegenerative diseases in mammals and are composed of multichain assemblies of misfolded host-encoded cellular prion protein (PrP). A common polymorphism at codon 129 of the PrP gene (PRNP), where either methionine (M) or valine (V) is encoded, affects the…

Case 1-2017: A 70-Year-Old Woman with Gradually Progressive Loss of Language
01/01/70 - Presentation of Case. Dr. Bradford C. Dickerson: A 70-year-old woman was seen in the memory disorders clinic of this hospital because of progressive cognitive difficulties involving word finding. She was interviewed with the assistance of her daughter. The patient had reportedly been well until…

Trial of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine
01/01/70 - More than 6 million children and adolescents in the United States have migraines. The majority continue to have headaches into adulthood, taking a toll on the U.S. economy of approximately $36 billion and resulting in substantial effects on quality of life. Pediatric clinical practice guidelines…

Pediatric Migraine Headache ? Still Searching for Effective Treatments
01/01/70 - Migraine headaches are common in children, adolescents, and adults. In children, migraines have a considerable effect on development, often leading to missed school days, educational delays, and decreased socialization. In adults, migraine headaches result in a considerable number of days lost from…

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