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The New England Journal of Medicine: Search Results in Endocrinology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Endocrinology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Bariatric Surgery versus Intensive Medical Therapy for Diabetes ? 5-Year Outcomes
01/01/70 - Observational studies and randomized, controlled trials, which have generally been short-term studies, have shown that bariatric surgery, when used specifically to treat diabetes, significantly improves glycemic control and reduces cardiovascular risk factors. In the Surgical Treatment and…

Intralymphatic Injection of Autoantigen in Type 1 Diabetes
01/01/70 - To the Editor: Residual insulin secretion decreases complications and improves quality of life in patients with type 1 diabetes. However, effective interventions to preserve residual beta-cell function are lacking. Antigen-based therapy requires adequate presentation to T cells. Treatment with…

Making the Connection
01/01/70 - Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information, sharing his or her reasoning with the reader (regular type). The authors? commentary follows. Stage. A 41-year-old man with a weight of…

Making the Connection
01/01/70 - A 41-year-old man with hyperlipidemia and a history of morbid obesity since childhood was referred to a surgeon for a weight-management consultation and consideration of bariatric surgery. The patient had tried dieting on his own and had also tried several commercial weight-loss programs with…

Mechanisms, Pathophysiology, and Management of Obesity
01/01/70 - Seven of the top 10 leading causes of death and disability in the United States today are chronic diseases (e.g. cancer and diabetes). Prevention and treatment of most of these conditions must address the close link with obesity. People who are overweight or obese account for more than two thirds…

Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors
01/01/70 - Neuroendocrine tumors of the midgut (which is defined as the jejunoileum and the proximal colon) commonly metastasize to the mesentery, peritoneum, and liver and are frequently associated with the carcinoid syndrome. Neuroendocrine tumors of the midgut represent the most common type of malignant…

The Large Pharmaceutical Company Perspective
01/01/70 - Large pharmaceutical companies conduct clinical trials to evaluate efficacy and identify safety issues for candidate drugs as effectively, efficiently, and expeditiously as possible, while addressing simultaneously the requirements of regulatory authorities across the globe. To put the fewest…

Myasthenia Gravis
01/01/70 - Myasthenia gravis is an autoimmune disease in which antibodies bind to acetylcholine receptors or to functionally related molecules in the postsynaptic membrane at the neuromuscular junction. The antibodies induce weakness of skeletal muscles, which is the sole disease manifestation. The weakness…

Breakthroughs for Whom? Global Diabetes Care and Equitable Design
01/01/70 - Ms. L. showed me the empty container of test strips and a box with butterflies on it. They were for a glucometer model I?d never seen before, called a FreeStyle. She explained that the machine had been given to her a few years earlier by a student philanthropic group from Arkansas on a "medical…

Wasting Energy to Treat Obesity
01/01/70 - The concept of enzyme therapy dates back to at least the 19th century, when pancreatic enzymes were offered to patients who had exocrine pancreatic insufficiency. In 1964, Christian de Duve suggested enzyme treatment as a therapeutic strategy for lysosomal disorder: three decades later,…

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