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Nejm News Une Mise à Jour The New England Journal of Medicine by Specialties

 


The New England Journal of Medicine: Search Results in Endocrinology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Endocrinology. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes
01/01/70 - The incidence of type 1 diabetes, which currently affects 29 million adults worldwide, is rising. In the United States, the number of patients with type 1 diabetes who are younger than 20 years of age may triple within 30 years. Less than one third of adults with type 1 diabetes achieve a glycated…

Adjunctive Treatments for Type 1 Diabetes
01/01/70 - The proliferation of new drug treatments for type 2 diabetes in the United States in the past 15 years, with more than 17 drugs approved in six new classes of antidiabetic drugs, has been promoted by several factors. First, the recognition of the importance of intensive glycemic control to reduce…

Necrotizing Soft-Tissue Infections
01/01/70 - Necrotizing fasciitis is a surgical diagnosis characterized by friability of the superficial fascia, dishwater-gray exudate, and a notable absence of pus. This and other necrotizing soft-tissue infections have multiple causes, risk factors, anatomical locations, and pathogenic mechanisms, but all…

Simulation of Growth Trajectories of Childhood Obesity into Adulthood
01/01/70 - In the United States, the prevalence of obesity has declined recently among children between the ages of 2 and 5 years and has stabilized among those between the ages of 6 and 11 years of age but continues to rise among adolescents and adults. Although the obesity epidemic has been well…

Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis
01/01/70 - Fatty liver disease is the most common liver disease in the world. About 25% of adults in the United States have fatty livers in the absence of excessive alcohol consumption, a condition termed nonalcoholic fatty liver disease. More than a quarter of adults with nonalcoholic fatty liver disease are…

Management of Acute Hip Fracture
01/01/70 - Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors? clinical recommendations. Stage. A 65-year-old…

ACE Inhibitors and Statins in Adolescents with Type 1 Diabetes
01/01/70 - Children with type 1 diabetes are at higher risk for long-term renal and cardiovascular disease and death than the general population, and adolescence is a period of risk for the development of complications, since adequate glycemic control is difficult to achieve. Rapid increases in albumin…

Nutritional Management of Chronic Kidney Disease
01/01/70 - Chronic kidney disease, defined as evidence of structural or functional renal impairment for 3 or more months, is generally progressive and irreversible, affecting multiple metabolic pathways. Altered protein and energy homeostasis, abnormal protein catabolism, acid?base derangements, and hormonal…

Evaluation and Management of Lower-Extremity Ulcers
01/01/70 - Lower-extremity ulcers are very common, with an estimated prevalence of 1 to 2% among U.S. adults, and they have a major effect on public health. Lower-extremity ulcers are divided into two groups ? leg ulcers and foot ulcers ? because of differences in causes, pathogenesis, and treatment. Even…

Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
01/01/70 - Fragility fractures are common and increase morbidity and mortality. Romosozumab (Amgen and UCB Pharma) is a new bone-forming monoclonal antibody that binds to and inhibits sclerostin, with a dual effect of increasing bone formation and decreasing bone resorption. In a randomized, controlled trial,…

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