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The New England Journal of Medicine: Search Results in Endocrinology
The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Endocrinology. NEJM ( is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice.

Evaluation and Management of Lower-Extremity Ulcers
01/01/70 - Lower-extremity ulcers are very common, with an estimated prevalence of 1 to 2% among U.S. adults, and they have a major effect on public health. Lower-extremity ulcers are divided into two groups ? leg ulcers and foot ulcers ? because of differences in causes, pathogenesis, and treatment. Even…

Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis
01/01/70 - Fragility fractures are common and increase morbidity and mortality. Romosozumab (Amgen and UCB Pharma) is a new bone-forming monoclonal antibody that binds to and inhibits sclerostin, with a dual effect of increasing bone formation and decreasing bone resorption. In a randomized, controlled trial,…

Romosozumab ? Promising or Practice Changing?
01/01/70 - Over the past decade, the osteoporosis landscape has changed. Even though more treatment options are available, fewer measurements of bone mass are being performed and fewer prescriptions for antiosteoporosis agents are being written ? the last probably related to concerns about known side effects…

Electrolyte Disturbances in Patients with Chronic Alcohol-Use Disorder
01/01/70 - Electrolyte disturbances are common occurrences in patients with chronic alcohol-use disorder, and the quantity and duration of a given patient?s alcohol consumption generally determine the clinical significance of these disturbances. Electrolyte abnormalities tend to be most severe in patients in…

Effects of Once-Weekly Exenatide on Cardiovascular Outcomes in Type 2 Diabetes
01/01/70 - The risk of death from any cause among persons with type 2 diabetes is up to twice that of the general population, and the risk of death from cardiovascular causes is up to four times that of the general population. Improved glycemic control has been shown to improve microvascular outcomes, but a…

Weight and Metabolic Outcomes 12 Years after Gastric Bypass
01/01/70 - The first surgical procedure performed specifically for weight loss took place in 1954. Since then, bariatric procedures have become less invasive and safer, and insights regarding the beneficial metabolic effects of such procedures have led to additional indications for these procedures.…

Case 28-2017: A 13-Month-Old Girl with Pneumonia and a 33-Year-Old Woman with Hip Pain
01/01/70 - Presentation of Case. Dr. Virginia M. Pierce: A 13-month-old girl was admitted to this hospital because of pneumonia. Nine days before admission, fever and vomiting developed in the child. The vomiting resolved after 2 days, but fever (with a maximum temperature of 39.7°C) continued, and the child…

Effects of Sotagliflozin Added to Insulin in Patients with Type 1 Diabetes
01/01/70 - The incidence of type 1 diabetes, which currently affects 29 million adults worldwide, is rising. In the United States, the number of patients with type 1 diabetes who are younger than 20 years of age may triple within 30 years. Less than one third of adults with type 1 diabetes achieve a glycated…

Adjunctive Treatments for Type 1 Diabetes
01/01/70 - The proliferation of new drug treatments for type 2 diabetes in the United States in the past 15 years, with more than 17 drugs approved in six new classes of antidiabetic drugs, has been promoted by several factors. First, the recognition of the importance of intensive glycemic control to reduce…

Liraglutide and Renal Outcomes in Type 2 Diabetes
01/01/70 - Persons with type 2 diabetes mellitus, particularly those with evidence of cardiovascular disease, are at high risk for chronic kidney disease. In most countries, diabetic kidney disease is reported to be the leading cause of dialysis-dependent chronic kidney disease. Efforts to blunt the global…

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