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The New England Journal of Medicine: Search Results in Endocrinology The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Endocrinology. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. Myxedema 01/01/70 - Figure 1. A Double-Edged Sword against Type 1 Diabetes 01/01/70 - Type 1 diabetes is an autoimmune disease leading to the destruction of insulin-producing pancreatic beta cells and subsequent hyperglycemia. Lifelong insulin treatment and long-term complications take a heavy toll on lives and bank accounts. The current epidemic in the Western world (with an… Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema 01/01/70 - Diabetic macular edema, a manifestation of diabetic retinopathy that impairs central vision, affects approximately 750,000 people in the United States and is a leading cause of vision loss. The costs associated with visual disability and treatment of diabetic macular edema are high. The increasing… Treatment Choice for Diabetic Macular Edema 01/01/70 - Macular edema is a common cause of vision loss in patients with diabetes. Chronic elevation of serum glucose levels leads to capillary damage that results in microaneurysm formation in the retina. Leakage from these microaneurysms leads to vision loss if the fluid involves the center of the fovea.… Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer 01/01/70 - The 10-year survival rate among patients with differentiated thyroid cancer that is refractory to radioiodine (iodine-131) therapy is 10% from the time of detection of metastasis.? Although treatment options have historically been limited, efforts have first targeted vascular endothelial growth… Acid?Base Problems in Diabetic Ketoacidosis 01/01/70 - This review focuses on three issues facing clinicians who care for patients with diabetic ketoacidosis; all of the issues are related to acid?base disorders. The first issue is the use of the plasma anion gap and the calculation of the ratio of the change in this gap to the change in the… Heparin-Induced Thrombocytopenia Presenting as Bilateral Adrenal Hemorrhages 01/01/70 - To the Editor: Heparin-induced thrombocytopenia is a prothrombotic disorder caused by platelet-activating antibodies that recognize platelet factor 4 (PF4)?heparin complexes. Heparin-induced thrombocytopenia is called "delayed onset" when it begins or worsens after the discontinuation of heparin… Wellens' Syndrome 01/01/70 - Figure 1. Biologically Inactive Leptin and Early-Onset Extreme Obesity 01/01/70 - Congenital leptin deficiency is a very rare cause of early-onset extreme obesity. It was first described in two extremely obese cousins from a consanguineous Pakistani family. The conditions of both children were characterized by the absence of leptin in the circulation as a result of a homozygous… Microbiota, Antibiotics, and Obesity 01/01/70 - Obesity is a major health issue worldwide, but the background for this condition is more complex than commonly assumed. Dietary and genetic factors have but partial roles in the development of obesity, which is why the focus in recent years has turned to the trillions of microbes residing in the… |
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