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The New England Journal of Medicine: Search Results in Geriatrics\Aging The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Geriatrics\Aging. NEJM (http://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. Should We Practice What We Profess? Care near the End of Life 01/01/70 - Physicians should be in a better position than people without medical training to judge the likely value of health care services available near the end of life. Yet several studies have revealed a disconnect between the way physicians themselves wish to die and the way the patients they care for do… Forty Years of Work on End-of-Life Care ? From Patients' Rights to Systemic Reform 01/01/70 - More than 2.5 million people die in the United States each year, most of them from progressive health conditions. Facing death is a profound challenge for patients, their relatives and friends, their caregivers, and health care institutions. Nearly 40 years of intensive work to improve care at the… Finding the Right Words at the Right Time ? High-Value Advance Care Planning 01/01/70 - When Ms. C. died, I was sad but not surprised. I had met her 4 years earlier, when I was an intern and she was the first patient who identified me as "my doctor." She did so enthusiastically, asking the inpatient medical teams who frequently cared for her to run every decision by me. As a trainee,… End-of-Life Advance Directive 01/01/70 - Case Vignette. Anne is a 59-year-old woman who is weighing her future and wondering whether she'll see her granddaughter grow up. She has breast cancer, and so far her treatments haven't beaten the disease or prevented its spread. She completed an advance directive when she was 50 years old, after… Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence 01/01/70 - The development of disease often involves dynamic processes that begin years or decades before the clinical onset. In many cases, however, the process of pathogenesis goes undetected until after the patient has symptoms and presents with clinically apparent disease. Cancer arises owing to the… Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes 01/01/70 - Cancer is thought to arise through the stepwise acquisition of genetic or epigenetic changes that transform a normal cell. Hence, the existence of a premalignant state bearing only the initiating lesions may be detectable in some persons who have no other signs of disease. For example, multiple… Clone Wars ? The Emergence of Neoplastic Blood-Cell Clones with Aging 01/01/70 - Blood cells originate from hematopoietic stem cells (HSCs). HSCs are infrequent (<2 per 108 bone marrow cells, or about 11,000 to 22,000 per person) and rarely divide. Because mutations occur with DNA replication during cell division, HSC quiescence maximizes genomic stability and thus safety.… Case 38-2014: An 87-Year-Old Man with Sore Throat, Hoarseness, Fatigue, and Dyspnea 01/01/70 - Presentation of Case. Dr. Leigh H. Simmons: An 87-year-old man with multiple chronic medical problems was seen in an outpatient clinic of this hospital because of sore throat and fatigue. The patient had been in his usual health until several weeks before presentation, when hoarseness, sore throat,… Postherpetic Neuralgia 01/01/70 - Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations. Stage. A 73-year-old… Deep-Brain Stimulation ? Entering the Era of Human Neural-Network Modulation 01/01/70 - Scribonius Largus, the court physician for the Roman emperor Claudius, used an electrical torpedo fish in 50 A.D. to treat headaches and gout. More than 1000 years elapsed before the idea of therapeutic brain stimulation was rekindled. In 1786, Luigi Galvani demonstrated that he could conduct… |
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